HotCommics
Mutation clustering approach to identify putative cancer driver genes
Description: This integrated workflow identifies mutational hotspot communities on protein structure to predict cancer drivers.
Citation
S. Kumar,D. Clarke, & M.B. Gerstein, Leveraging protein dynamics to identify cancer mutational hotspots using 3D structures, Proc. Natl. Acad. Sci. U.S.A. 116 (38) 18962-18970