Frustration

Structural genomics method to priortize missense mutations

Description: This repository contains source code for workflow evaluating the change in Localized frustration index of a protein residue upon mutation.
Authors: Sushant Kumar, Declan Clarke, Mark Gerstein
Lab: Kumar
Keywords: Genomic Analysis, Statistical Analysis
Implementation Language: Python
Licensing: GPL-3

Citation

Sushant Kumar, Declan Clarke, Mark Gerstein, Localized structural frustration for evaluating the impact of sequence variants, Nucleic Acids Research, Volume 44, Issue 21, December 2016, gkw927.