PeaKO Data

Description: PeaKO analysis of 8 sequence specific transcription factors (ATF3, ATF4, CHOP, GATA3, MEF2D, OCT4, SRF, and TEAD4). We evaluated our methods on these datasets, supplementing CentriMo with the collection of vertebrate motifs from the JASPAR 2016 database. Each transcription factor in our WT/KO datasets contains a corresponding motif within the JASPAR database. We used these JASPAR motifs as our gold-standard known motifs, and compared their rankings across methods. As a control, we processed the WT dataset alone through the same pipeline steps without any KO data.