Single-cell multi-omics profiling of glioma cells

Description: We profiled CD45- enriched, viable cells from GBM (n = 7) and IDH-MUT (n = 7) primary samples with multi-modality single-cell sequencing of scDNAme (by reduced representation bisulfite sequencing [RRBS]) and scRNAseq (Smart-seq2).

Authors:

Chaligne, R., Gaiti, F., Silverbush, D. et al.

Lab: Gaiti

Release Date: 2020

Keywords: transcriptome, methylome, single cell

Hosted on GEO

Citation

Chaligne, R., Gaiti, F., Silverbush, D. et al. Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states. Nat Genet 53, 1469–1479 (2021). https://doi.org/10.1038/s41588-021-00927-7

DOI

14 Samples

Datatype:scRNA-seq, scDNAm-seq

Species:Human

Disease Type:Glioblastoma (GB)

Contact

This dataset is available by request only.

Contact: Federico Gaiti

Contact email: Email