Single-cell multi-omics profiling of glioma cells
Single-cell multi-omics profiling of glioma cells
Description: We profiled CD45- enriched, viable cells from GBM (n = 7) and IDH-MUT (n = 7) primary samples with multi-modality single-cell sequencing of scDNAme (by reduced representation bisulfite sequencing [RRBS]) and scRNAseq (Smart-seq2).
Authors:
Lab: Gaiti
Year: 2020
Keywords:
Citation
Chaligne, R., Gaiti, F., Silverbush, D. et al. Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states. Nat Genet 53, 1469–1479 (2021). https://doi.org/10.1038/s41588-021-00927-714 samples
Sample Type:N/A
Species:Human
Datatype:Single-cell DNA Methylation, single-cell RNA-seq
Technology:Illumina NovaSeq 6000