Single-cell DNA methylomes of normal B and CLL cells
Single-cell DNA methylomes of normal B and CLL cells
Description: Multiplexed reduced representation bisulfite sequencing (MscRRBS) of healthy donors B cells and CLL patient samples. We profiled the single-cell DNA methylomes of 831 normal B cells from six healthy donor samples and 1,821 cells from 12 primary IGHV mutated and unmutated CLLs.
Authors:
Lab: Gaiti
Release Date: 2018
Keywords: transcriptome, methylome, single cell
Citation
Gaiti, F., Chaligne, R., Gu, H. et al. Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia. Nature 569, 576–580 (2019). https://doi.org/10.1038/s41586-019-1198-z18 Samples
Datatype:scRNA-seq, scDNAm-seq
Species:Human
Disease Type:Chronic Lymphocytic Leukaemia (CLL)